STAT5 Transkriptionsfaktoren im braunen Fett: „Schalter“ gegen Übergewicht?
After publishing their paper in “Molecular Metabolism”, Katrin Spirk and Doris Kaltenecker accomplished to publish their research success once more in the German magazine “Nutrition News”.
While Katrin is doing her PhD here with us in the Moriggl lab, Doris Kaltenecker is currently doing a Post Doc in the group of Prof. Dr. Stephan Herzig at the German Research Center for Environmental Health (Helmholtz Zentrum München) in Munich.
Despite the recurring lockdown measures that make working in research particularly challenging nowadays, PhD students from the Moriggl lab nevertheless participated in the Cytokine meeting 2020, that took place online from the 1st until the 4th of November.
Christina Wagner presented our model systems for JAK/STAT gain and loss of function mutations in the form of a lightning talk, which is a pre-recorded talk of 3 minutes/3 slides.
Tobias Suske recorded and uploaded an insightful talk about his research on STAT5BN642H driver mutations.
Christina and Tobi engaged in the online Cytokine meeting.
Tobias Suske receives Milstein Abstract Award for Cytokines 2020 Virtual Meeting
The Award Committee of the International Cytokine and Interferon Society (ICIS) selected Tobias for a Milstein Abstract Award in the amount of $500 in recognition of his presentation. The talk entitled “The Activating STAT5BN642H Driver Mutation Disrupts T Cell Development Progressing to T Cell Neoplasia” was given in the session “Structure-Function and Systems Biology of Cytokine Actions”.
Congratulations Christina and Tobi, and thank you ICIS for this great event! 🙂
The Special Issue “Targeting STAT3 and STAT5 in Cancer”, edited by Prof. Dr. Richard Moriggl, Prof. Dr. Patrick Gunning and Prof. Dr. György Miklós Keserü was published with 26 papers in Cancers (peer-reviewed Open Access journal of oncology published monthly online by MDPI). Read the full text of the papers at the following link:
We, the Orlova Group Inhibitor Team, have used the Covid-19 times productively. Testing new compounds for STAT5 inhibition, we have done over 300 cytotox assays together in shift work.
Our group successfully published a paper on STAT5 signaling in lipid metabolism in the journal “Molecular Metabolism”.
Doris Kaltenecker and Katrin Spirk were working together on this project and investigated the function of STAT5 in brown adipose tissue thermogenesis, as well as its role in the brown remodelling of white adipose tissue. They demonstrate in their work the importance of STAT5 for the functionality and the β-adrenergic responsiveness of thermogenic adipose tissue.
The Neubauer Lab 