
In the research work „The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease” Anna could show that hyperactivation of ERBB receptors and STAT3 can lead to transmission of tumours in the Tasmanian Devil. Congratulations, Anna!

In the research work „The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease” Anna could show that hyperactivation of ERBB receptors and STAT3 can lead to transmission of tumours in the Tasmanian Devil. Congratulations, Anna!
The project “Novel individualized therapies in JAK/STAT driven T cell malignancies” (Acronym: JAKSTAT-Target) aims to investigate the role of the JAK-STAT pathway in mature T cell lymphomas and to identify potential drugs and drug synergies targeting this pathway.
The consortium of six research groups from Vienna (Heidi Neubauer), Helsinki (Satu Mustjoki, Tero Aittokallio), Cologne (Marco Herling) and Toronto (Patrick Gunning, Benjamin Haibe-Kains) will focus on the entities of T cell prolymphocytic leukemia (T-PLL) and T cell large granular lymphocyte leukemia (T-LGLL), both showing a high incidence of missense mutations in JAK-STAT pathway genes.
The consortium, led by Satu Mustjoki, will uncover new mechanistic insights into these rare diseases and implement machine learning algorithms to predict synergistic effects from genomic, clinical and in vitro drug sensitivity data, ultimately integrating these data into clinical trials.
For more details, please visit the JAK STAT Target Consortium website, the ERA Per Med Newsletter or the affiliated Twitter profile.


Anna Orlova had a productive research stay at the Hungarian Academy of Science in the group of Professor Keserü from the 11th till the 15th February 2019. On the 14th/15th February a conclusion meeting with Professor Moriggl, Dr. Bajusz and Mag. Ruckenbauer took place.

Richard, accompanied by Heidi and Tobi, enjoyed some days at the 2019’s Midwinter Conference in Tirol.

Besides presenting two posters at the event and extensively discussing recent topics in Immunology, they could also enjoy some winter sports in the beautiful Seefeld. Thank you for organising this unique and inspiring conference!
